Skeletal muscle actin mRNA. Characterization of the 3′ untranslated region
نویسندگان
چکیده
منابع مشابه
Skeletal muscle actin mRNA. Characterization of the 3' untranslated region.
Plasmids p749, p106, and p150 contain cDNA inserts complementary to rat skeletal muscle actin mRNA. Nucleotide sequence analysis indicates the following sequence relationships: p749 specifies codons 171 to 360; p150 specifies codons 357 to 374 together with 120 nucleotides of the 3'-non-translated region; p106 specifies the last actin amino acid codon, the termination codon and the entire 3' no...
متن کاملThe 3'-untranslated region of ADAMTS1 regulates its mRNA stability.
ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin motifs 1) is an inflammatory-induced gene. We have previously reported that ADAMTS1 was strongly but transiently expressed in the infarcted heart. In this study, we investigated whether a 3'-untranslated region (UTR) affects the mRNA stability of this gene. When stimulated with tissue necrosis factor (TNF)-alpha, the expression le...
متن کاملTransdifferentiation of chicken embryonic cells into muscle cells by the 3' untranslated region of muscle tropomyosin.
Transfection with a plasmid encoding the 3' untranslated region (3' UTR) of skeletal muscle tropomyosin induces chicken embryonic fibroblasts to express skeletal tropomyosin. Such cells become spindle shaped, fuse, and express titin, a marker of striated muscle differentiation. Skeletal muscle tropomyosin and titin organize in sarcomeric arrays. When the tropomyosin 3' UTR is expressed in osteo...
متن کاملSarcoplasmic reticulum Ca pump mRNA stability in cardiac and smooth muscle: role of the 3 -untranslated region
Misquitta, Christine M., James Mwanjewe, Lin Nie, and Ashok K. Grover. Sarcoplasmic reticulum Ca2 pump mRNA stability in cardiac and smooth muscle: role of the 3 -untranslated region. Am J Physiol Cell Physiol 283: C560–C568, 2002. First published April 18, 2002; 10.1152/ ajpcell.00527.2001.—Stomach smooth muscle (SSM) and left ventricular muscle (LVM) express the sarco(endo)plasmic reticulum C...
متن کاملSarcoplasmic reticulum Ca(2+) pump mRNA stability in cardiac and smooth muscle: role of the 3'-untranslated region.
Stomach smooth muscle (SSM) and left ventricular muscle (LVM) express the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) pump gene SERCA2. Alternative splicing yields two major isoforms, SERCA2a in LVM and slow twitch muscle and SERCA2b in SSM and most other tissues. The splices have different 3'-untranslated regions (UTR) and also encode proteins that differ slightly in their COOH-terminal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1981
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/9.3.579